default homepage error

[ASM Don Toner]

After installing messenger, when I first opened IE it is running the
following site: http://runonce.msn.com/en/runonce.asp . When I click on
keep current, there is a javascript error at line 297....
oHomePage.setHomePage(homePageURL);
permission is denied....
what setting do I have to change to allow this to run so I can reset my
homepage... it is currently "greyed" out in the internet options under the
tools...
Thanks....