T wrote:

Crap! I am staring at the requirements:

Requirements

Desktop computer with one available PCIe slot 4x or larger
Windows® 10 (32-/64-bit) / 8.x (32-/64-bit)

If I don't get it to work out the box, I will have major egg on my face.

I hate when I come across an older system with only USB2 and the
customer need a fast backup system.

Does the mobo support eSATA (on which you could use a shielded SATA
cable)? Does the external drive's enclosure have both USB2/3 and eSATA
ports? If it has eSATA, go with that. You sure the external
USB-attached drive supports USB3? Else, you'd spend time and money
adding USB3 to the computer but the external drive can't use it.

USB2 is [theoretically] 480 Mbps. Does the customer's computer have a
NIC that can support 1 Gbps? If so, how about a NAS drive? Obviously
the customer cannot swamp their network with traffic due to the
collision detection and conflict handling of the Ethernet protocol. If
he downloads huge files from the Internet or passed them between his
intranet hosts, issues huge print jobs, or otherwises dumps on his
network then the NAS drive will get slower because its portion of the
remaining bandwidth gets smaller.

USB2 is 0.48 Gbps. NAS would be 1 Gbps. USB3 would be 5 Gbps. eSATA
would be 6 Gbps. What is an option and feasible depends on whether the
exiting USB2 external drive must continue being used or if different
external storage media is permitted.

Have you tried the Intel drivers (if the mobo has an Intel chipset) in
Windows 7 to see if you can get the Asmedia card to work properly?
Seems you were willing to try them with an unknown candidate replacement
card.