UPDATE:

Start Run commands associated with the default Microsoft web browsers:
o Win+R microsoft-edge:// == gives you a choice of Edge browsers if both
o Win+R microsoft-edge: == brings up the current Edge browser if one
o Win+R iexplore == brings up Internet Explorer (if enabled)
o Win+R microsoft-edge:about:blank == opens default edge to a blank page
o Win+R http://google.com == brings it up in the default browser
o Win+R microsoft-edge://google.com == brings it up in the default Edge
o Win+R cmd start microsoft-edge: == brings up the default Edge
o Win+R cmd start microsoft-edge:http://google.com == opens that page
o Win+R powershell start microsoft-edge: == brings up the default Edge
o Win+R explorer microsoft-edge: == Windows file explorer address bar
o Win+R shell:AppsFolder\Microsoft.MicrosoftEdge_8wekyb3d8 bbwe!MicrosoftEdge
o Win+R %windir%\system32\cmd.exe /c "start microsoft-edge:http://google.com"
o Win+R %comspec% /c start shell:AppsFolder\Microsoft.MicrosoftEdge_8wekyb3d8 bbwe!MicrosoftEdge http://google.com
etc.

Note: Those latter entries are useful to create TARGETs to specific
web-page shortcuts, (where you can combine commands to quickly open any
number of web pages):
o What syntax combines 2 commands into a single shortcut TARGET line?
https://groups.google.com/forum/#!topic/alt.msdos.batch/azQbz6D_v0Y

You can even create an "edge" command to enable "Win+R edge", e.g.,
o Win+R shell:appsfolder
o Create a System32 (path) shortcut named "newedge" and "oldedge".
o Win+R newedge == you can also add to the "app paths" registry key

See details in:
o Tutorial to set up 3 Microsoft web browsers to work concurrently
https://groups.google.com/forum/#!topic/alt.comp.freeware/fZlJTYRxYFg

And in:
o Over 250 Start Run commands (please improve this Start Run commands list)
https://groups.google.com/forum/#!topic/microsoft.public.windowsxp.general/cc1lGn3ty0E
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