On Wed, 6 Dec 2017 18:03:49 -0500 "Jason" wrote in
article

The machine my wife uses came with 10 and the all the updates have
installed without a hitch. But after the latest one, there is a minor
issue with Outlook 2016 for which I've yet to find an answer. When it is
first opened, all looks normal and new email arrives and shows in the
Inbox. But you cannot do anything at that point. It is as if everywhere
that should be "clickable" isn't - the mouse cursor doesn't change shape,
the buttons don't do anything. The only recourse is to close Outlook and
open it again. Then everything works. ?

Forgot to mention. I tried the Repair option for Office 365 in Programs
and Features. There are two choices - a "quick repair" one and a long one.
Neither made a difference.